Plants are a remarkable resources for our everyday lives with their richness; they are source of food, feed, raw material for wide variety of industries. With the accumulating scientific knowledge about plant biology and plant genetics, environmentally-friendly and ration solutions for agriculture, environment and industry will be beneficial for the humanity and for the planet.

Plants are in continuous interaction with their surroundings. Abiotic factors such as heat, water content, wind, salt concentrations, can be rapidly changing in the environment plants are growing and thus plants need to adapt to these changes rapidly by altering their metabolisms and their gene expressions. Transcription factors are one of the main factors contributing to change in gene expression for abiotic stress response and adaptation. Hence, one of our main research topic is enlightening relationship between transcription factors and abiotic stresses in agriculturally important monocots which will contribute to agricultural biotechnology.

On the other hand, plants have cellulose based cell walls, surrounding their cells, giving shape and acting as a barrier, along many other roles. The plant cell walls are one of the most abundant biomass resource on our planet. Understanding their synthesis and their modifications throughout the plant's life will help us use this biomass more efficiently. Also, understanding the cell wall regulation and driving forces behind the regulation will guide us in many different topics, including abiotic stress response and molecular breeding.

Thus, our main research focuses are:

Researching plant cell walls from the aspect of cell wall modifications, Answering questions about how transcription factors are playing role in plant development and plant abiotic response.

• Plant Biotechnology
• Plant Cell Walls
• Plant Transcription Factors
• Plant metabolites and metabolic engineering

• Work Experience
• Assistant Professor, 2021- Present
  Molecular Biology and Genetics, Bahçeşehir University
  
• Specialist, 2020-2021 
  Nobel Pharmaceuticals Biotechnology
• Research Assistant, 2018-2020 
  Plant Cell Biology and Biotechnology Institute, Heinrich-Heine University
  
• Education
• PhD candidate, 2011-2018 
  Biotechnology Program, Yeditepe University
  
• Bachelor studies, 2007-2011 
  Molecular Biology and Genetics, İstanbul University
  

1. Akdemir Koç H., Seven M., Derman Ü. C, Harvey A.J. In silico analysis of XTH gene family from barley (Hordeum vulgare L:) and their comparative expression analysis during germination. Turkish Journal of Botany, 2021, DOI: 10.3906/bot-2108-31
2. Seven, M., Derman, Ü.C. and Harvey, A.J. (2021), Enzymatic characterization of ancestral/group-IV clade xyloglucan endotransglycosylase/hydrolase enzymes reveals broad substrate specificities. Plant J, 106: 1660-1673. https://doi.org/10.1111/tpj.15262
3. Özcan, E, Seven, M, Şirin, B, et al. Dynamic co‐culture metabolic models reveal the fermentation dynamics, metabolic capacities and interplays of cheese starter cultures. Biotechnology and Bioengineering. 2021. 1– 15
4. Seven M, Akdemir H. DOF, MYB and TCP transcription factors: Their possible roles on barley germination and seedling establishment. Gene Expression Patterns, 2020. 37.
   
5. Celep, E., Seven, M., Akyüz, S., İnan, Y., Yesilada, E. Influence of extraction method on enzyme inhibition, phenolic profile and antioxidant capacity of Sideritis trojana Bornm. South African Journal of Botany, 2019. 121, 360-365
   
6. Ramirez, V., Wang, S., Robertz, S., Seven, M., Kraemer, F., Kuhn, B. M., ... & Pauly, M. 2023. A large-scale forward genetic screen for maize mutants with altered lignocellulosic properties. Frontiers in Plant Science, 14, 783.

1. Seven M, Harvey A.J. (2024) Pectins: Transcriptomic analysis of genes involved in their synthesis and modifications during barley seedling development. 9th Edition of Global Conference on Plant Science and Molecular Biology. 16-18 September 2024. Rome, Italy
2. Akdemir H, Akyol Z, Türkyılmaz T, Seven M (2024) New approaches for efficient anthocyanin production in E. coli. 5th International Eurasian Conference on Science, Engineering and Technology (EurasianSciEnTech 2024), June 26-28, 2024, Ankara. Proceeding book. p.59.
3. Celep E., Seven M., Akyüz S., İnan Y., Yeşilada E. Comparison of extraction methods of Sideritis trojana Bornm. in terms of enzyme inhibition, antioxdant activity and phenolic profile. Advances in Lamiaceae Scene Symposium, Turkey, 2017
4. Seven M., Derman Ü.C., Fettahoğlu N.R., Harvey A.J., Akdemir H. Gene Expression Profiles of Xyloglucan Endotransglycosylases (XTH) during barley germination. VISCEA Plant Genes and "Omics": Technology Development. Vienna, Austria, February 11-12, 2016.
5. Seven M., Tüzün D., Harvey A.J. Seeking the evolutionary origins of xyloglucan endotransglycosylase enzymes: Analysis of xyloglucan-active enzymes. Gordon Research Conference. Plant Cell Walls, From Genomes to Function, Waltham, MA, USA. July 12-17, 2015.
6. Seven M., Harvey A.J. Characterization of xyloglucan endotransglycosylases from various plant species. Gordon Research Seminar. Plant Cell Wall Research: From Structure to Sustainability, Waltham, MA, USA, July 11-12, 2015.
7. Akdemir H., Seven M., Kıtır N., Harvey AJ. Assessment of toxicity of carbon nanotubes (SWCNT, MWCNT and MWCNT-COOH) on barley germination. 10th Nanoscience and Nanotechnology Conference. Istanbul, Turkey, 17-21 June 2014.
8. S. Karaer, M. Seven, S. Sisko, B. Palabiyik, M. Pekmez and A. Topal. Sarikaya, Oxidative stress studies with IMPDH-overexpressed S. pombe, The Sixth International Fission Yeast Meeting, Boston, MA, USA, 25-30 June 2011.

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